ABC Executive Director’s Editorial Emphasizes Published Clinical Trials Supporting the Therapeutic Benefits of Leading Herbs

(April 23, 2009) The March/April issue of Alternative Therapies in Health and Medicine features a guest editorial by ABC Founder and Executive Director Mark Blumenthal, in which Blumenthal addresses one of the primary inaccuracies promoted by some critics of herbal medicine: the myth that clinical trial evidence shows many popular herbal preparations to be ineffective.

In his editorial, titled “Systematic Reviews and Meta-analyses Support the Efficacy of Numerous Popular Herbs and Phytomedicines,” Blumenthal discusses how the public perception that certain herbs do not work has been misled by highly publicized randomized controlled trials (RCTs) with negative outcomes. These include RCTs of preparations made from herbs such as St. John’s wort (Hypericum perforatum) to treat symptoms of mild to moderate depression, and echinacea (Echinacea spp.) to deal with upper respiratory tract infections related to colds and the flu.

Blumenthal goes on to cite numerous recently-published systematic reviews and meta-analyses of RCTs in which the above-mentioned herbal preparations were significantly more effective than placebo. In addition, he points out that some trials found herbs to be as effective, and safer, than conventional pharmaceutical medications used for the same purposes. Also included in this discussion are reviews of RCTs of garlic (Allium sativum) for lowering blood pressure, Asian ginseng (Panax ginseng) for erectile dysfunction, and hawthorn (Crataegus spp.) for aspects of congestive heart failure.

Blumenthal concludes the essay as follows:

All too frequently, however, glaring exposure in the media of one high-profile negative trial becomes “the conversation,” with the larger body of clinical research, as well as highly relevant epidemiological and other non-RCT-based data, being relegated to a cognitive Twilight Zone. Even critics of CAM and herbal medicine in particular, frequently fall into the trap of taking refuge under the high-profile negative trial in attempts to dismiss an entire herbal category and, by extension, all herbal preparations in sweeping generalizations that would never be countenanced in a freshman-level course in logic, much less the “evidence-based” practice of medicine.

Click here to read a PDF of the editorial is available on the Alternative Therapies website.

Reference
Blumenthal M. Systematic reviews and meta-analyses support the efficacy of numerous popular herbs and phytomedicines. Altern Ther Health Med. 2009;15(2):14-15.

Prince Charle's New Detox Product Toxic?

According to a press release posted March 23 by the American Botanical Council:

On Friday, March 12, ABCNews.com’s Health section published a story on the controversy surrounding detoxification now brewing in the United Kingdom. The American Botanical Council’s Founder and Executive Director Mark Blumenthal is extensively quoted in the article.

The controversy is related to the launch of a new line of herbal products by Duchy Originals, a company that promotes organic and sustainable food production, founded by the Prince of Wales in 1990.^1,2 The new herb line, Duchy Herbals, was launched in January 2009.² So far Duchy Herbals includes an Echinacea-relief tincture (containing the root of Echinacea purpurea), a Hyperi-lift tincture (containing St. John’s wort, Hypericum perforatum), and a Detox tincture containing artichoke (Cynara scolymus) leaf and dandelion (Taraxacum officinale) root.

The ABC News article was stimulated by an article in the UK containing criticism by Prof. Edzard Ernst, MD, PhD, a widely-cited author of clinical trials and systematic reviews on complementary and alternative medicine modalities, of a detox product.

For the sake of perspective, it is constructive to know that the Echinacea-relief and Hyperi-lift tinctures are the first herbal tinctures produced in the United Kingdom to be registered under the Traditional Herbal Products Directive (THMPD), a recent regulation applying to all European states.² The THMPD allows herbal products to be registered under medicines law. To earn a license a company must submit a complete file to the Medicines and Healthcare Regulatory Authority (MHRA) containing extensive evidence of a product’s traditional use, safety, and quality.

However, the detox tincture requires no such licensing from MHRA because it is classified as a food supplement. The “detox” product is intended to aid people in the removal of toxins from their bodies. [...]

The article quotes Blumenthal and Dr. Lee as follows:

Mark Blumenthal, founder and executive director of the Austin, Texas-based herbal medicine think-tank American Botanical Council, said that part of the thrust behind the detox movement is the idea that the food supply and environment of today expose people to higher levels of chemicals and pollutants than in the past.

"Many people—rationally or irrationally, correctly or not—believe strongly that they must detoxify their bodies to give themselves that extra edge to get rid of [these chemicals]," he said. "There is probably a healthy and rational basis for some of this, though some people take it a bit too far."

And Dr. Roberta Lee, vice chair of the Department of Integrative Medicine at Beth Israel Medical Center in New York City, said detoxification as a concept may be getting an undeservedly bad rap.

"Detoxification is a natural process that occurs in the body, though it is not labeled as such in the medical profession," she said. "The idea that detox is a silly notion, I think, is a fallacy."

Blumenthal and Lee were further quoted in the article which can be accessed in full here.

References

¹ Childs D. Prince Charles’ herbal products stir controversy. ABCNews.com. March 13, 2009. Available at http://abcnews.go.com/Health/WellnessNews/story?id=7071267&page=1. Accessed March 16, 2009.
² Duchy Originals encourages consumers to adopt an integrated approach to healthcare with launch of duchy herbals [press release]. East Twickenham, London, England: Duchy Originals. January 22, 2009.

© 2009 American Botanical Council: http://cms.herbalgram.org/press/2009/PrinceCharlesDetox.html